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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5456b0be2336e186b373a2686a214388a05164a9ac24ee1a9cdb3e8d8e671e' 
  AND token = 'FMONHfVvxhYqAbvEjzAUfxIs8R+bSU5W13TtPFtNZO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}