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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c67e3d0379142b4162f7028cde25ea91b16783da2a906b5c266a3a1c246b854' 
  AND token = 'mYr9156Fq7cnbnBW0Rm0dn6zhQ9if5xBv1Gs78mEYcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}