SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcd75c6bd3a1c9f3e838a735d1315dcecd41452086e0c9f9982a7ff427031215' 
  AND token = 'EGBCbTkR87AfDmrCg4a6PX3sgM6+1rrk5+KqbtKzbPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}