SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f7295b3765448f4b5e300165c8d73edd2cc6e5e97b3781812308b155cd6591' 
  AND token = 'YuuQUP3pcHpu3tnhoEkAp6AyZ/wNn81+13GuIm5dtM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}