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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f517b8a23b63b1d09eb32a4991fc6143a6dd253145d1dd53d8adfac69fc66b3' 
  AND token = 'vg17S0Gy2wZAhf0kHwDP9LTkkdhY8E+IwVji3t5KGiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}