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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad27e6c015aa395c67a2d5665c6831732e03f7a892668bb953e85a6ec0db525' 
  AND token = 'HoAiOlDqpbG7uHbkq/hQh/Ou0sG47mHY04ueWUd9+0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}