SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5753ac816ddf5a438d2052bbfbbb78c436c944a1c68d4394bd85275a380f5b6' 
  AND token = 'lheo4KUfz4wdAeJOvs962QaaseutIrxiEWRUTvEWfzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}