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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8f59797ae865cf7472189097b6b007d526f1c0204af257365f9640378abc25' 
  AND token = 'nyIbGyfoGxi0a+wia1ZzVt221s2fSRDaC3mXzhiev+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}