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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3dd59eee8428015771dd18ffec73bd0fe5fa8cfff1fb0249e686af5fbbc565' 
  AND token = 'TL05McHB+bfMK3H/WTvL7rf0ff/p1r0lfIpdFAc9Ij8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}