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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2cd43cf1876c0a68bcdab861f8fd7e3d05f17c7668472c5afe7d72f029c441e' 
  AND token = 'nSOLucO2AffZ2Gz9I1k85DoGZk8PhGeWHiRPAcnMSjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}