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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cedbbc992d2b6b35611c871dfe68847bf1d312320c89dde24fac145463c1bb7' 
  AND token = 'HDWEv1y6O0fKpzkEi5ZcXxlgYHEXmypsK6BuaL0UMPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}