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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2759d0b93710c7c182e9f78fbfb8abe2f19709b3aa769e8fe907c94f1dd304d4' 
  AND token = 'R2Q5ZMs16sj90L1F8d/3QmtVtSDm+w4bvmC6WYOJI2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}