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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24df6d83dfca1d0dc393ffa6fdea63039092b0afcbe99cf771049ac38d7c5a7e' 
  AND token = '+DJGakTvhTIgS9cQKuxzBE9Uyo9PkcZvKDnnyr6LHqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}