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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc0cf029b81018df15c4e22375e2ee6d61547ebf1cd96063154ce6f09e5a147' 
  AND token = 'WOSIPCekug1Z7VE2JtktjhHVbPBTu9HN8BdZmp41Gj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}