SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40dd35153615236b8c41060e4425eb92da201fe20c54985097836d618c097f8' 
  AND token = 'QBky3Df2mkAZzvOWFdgioMD2pu5ddov29KZeOaH+Beg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}