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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5e908bc5a89ed62875b477ae3db8857295af59e69ed018add2551eb3110cff' 
  AND token = 'TO1T+bLP0rlbnK3nZh7uxsAnUacWwQBoMktqhZmQhKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}