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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86405fd9af38dfa48c36b1f585afd0d33b8a870be33983b7c259bd88d572f379' 
  AND token = '8lPaXUZBYxwJnjDa8R7asmYrxEuAY0a6OXFfVhVek7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}