SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52173d271795995fe1a29b434f997b442532a1b040aef688ae71f76591604730' 
  AND token = 'xPjHWJfPZenQ7hTEWb4IHKFdrHpGMv46xPltSBWgggQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}