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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c7a5c2a16df9cdc2c925eac42122c152f49e6fde544814e3cc9d0e53e46ce8' 
  AND token = 'PKrArrHjpI7WCfTYLfl601yxaRey5L/qW+gCIiCDCGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}