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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5466ca7174305256d1817b7c558522f09f8c87602d4f474577a65792b745493e' 
  AND token = 'CFJ7ufuUnp6k4Yinyeh14SN3sGGNSi3Ap0mecBKKLpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}