SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ddafce6096e12bc49d7dc97d931953886a51b393f197ac527b8000d2c16d34' 
  AND token = 'of8mMOR4kdxLkNMpEyyFO206SiK1eOKRg4dXH8TS3ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}