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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d487b78e1e1eae9de4512d5150b14848bf3baa51112340d92c0506fa7b075a9' 
  AND token = 'MM4Mi0SDxt2yrDux9VZMRgolwY9BrztvOS20PiXKhko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}