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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b45066074e643572aa8a74f6c2f87980e856f47fb60f64ae325888483e7567a' 
  AND token = 'laYa6+w7cXxKyagpR8LCiYNn29WPs+Id8wqPYH6wdIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}