SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a08a7cd885d77521ffa6b88fe1cf807a8f180d089d1b93d8188bde00215b537d' 
  AND token = 'iMvv3eD/1K+bjKv/uwyL5tJH/xyLnUXsR2SV1T7V9Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}