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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26bdd401f064972d0f6c3e9948a25d066ad1613cf10b93e865b37a1221c08880' 
  AND token = 'ZUmrSMymoiq3Y4teu1eXGZPY8gAzcti96v2bCokrzbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}