SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10defb258274ada4b5bee57a6ad6ce11f5e88cce2c835b6adc9b794ae7ea3af2' 
  AND token = '2EpIBSzE3YJXsvnWwHSF4atp/RNRQ8RdE2FrRs9q+Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}