SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7baf7e957477f07349888d4555a736d890fd971e4530b0dd71b4cd053b47fc' 
  AND token = 'cMSmXqPYYgZ6CmQhN4XbWD2uJnJsyZW5bV0YFavY0k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}