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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e1180651363b564c4f3f8c077bc6c63c4852f1b70b4e6c2b4704243cdaa116' 
  AND token = 'L1lhy59ygLS8vNXtalgNXHli6WNMb6qHrrZ2MBtsmfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}