SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46aede1cc0f8e82d5dd310a9fb72709c12cff1e2820a8d67728fe9abc54b61e' 
  AND token = 'NtJaw12jqKLmmtQyfgv4BwQTts3eXnHD0ZC4Hze4oLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}