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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538f0434f01f0f3e88b70013fc4c7b47b33e712e733e43f6fbb78e6a3d0a3bb1' 
  AND token = '8AdtH+Gj4P+TNGRWJ6F13P8vRa1F28x1X8ziHf/9qYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}