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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37bf889789a4abb82b237e90400a7b5add616fb0df227fa1dfb18e0c18cffc76' 
  AND token = '1N5UwMWct8mMRw3waEGnp4E2uEDlTLN51w99aeW/N44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}