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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be37baed6949874f101d62a5208b0322ec08526f1977a3f5acc6967b88700644' 
  AND token = 'Vo3COVQOtRrrDjT8DKZxCyhe17ZVNwvGbMyzTdA5Qtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}