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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a4416f35944e0a9052d9c34b9e87ade4023217a355528a514866b78437cd741' 
  AND token = '9zRx0HmVyx37yAkL8Qqe1aJU53x3KDhwYlLRgvgaHFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}