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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b140d69e7648d683bce5681ef5d33575e1b08c59c3d11cbddd641f20387c42f8' 
  AND token = 'NzkIkz/SIUdzMw2tzeZD1o+9ukoixBfWBlA/ZTe7w9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}