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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd1f6a24b602ee031326cf8f6ff4da2b7653f58d71e1556d5d1831b14d9bb31' 
  AND token = '1WP3DLw2kwdSZc4si8bAyzsp5qk5oRWuPf+XFNOUBos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}