SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949996e8638b3582af5218910a49f0fbd78e018bbaeee37d053b8150cc200918' 
  AND token = 'QqN7QiOnNEqrXncRxQe6uWetZmtcCiRG4l+w+bk9vd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}