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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4786ead24231ed091f1cfa5864df10de3a2c071c27779ba6b20d11cc0e6c8223' 
  AND token = 'nkPM+pEyOpZKbrSKeBA9HNZXc7ZnGP9ByfSxFymBLgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}