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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801c10be58beb1ec1267584f9e03d783e35c218760cc1ccfed7401795a9dd0e5' 
  AND token = 'kKf5UDNYy9c9nis1hGc0jWJgh6iZWFB48vE5ArbiH4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}