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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b046a7304eb31cefdbfa89a4d08ffbe503073a0044dd567b4aeeb09e2f8ff798' 
  AND token = 'ei2JDjMt0gAZXDLa8MjEGiZENSrDiEvPMTcIYdd7wlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}