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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f121852b16cb3317fdda6bf8d5c0582fdff24233584bbd9c5c705e5d4db804f' 
  AND token = 'SIT6rcWRHNeUDURjT9rscsgCWUVIYVbbALxPiiw+djo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}