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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e6cbc285cf2b7379557fcc72b8f57b433455819e3cb963f1bc6de0bdbe5556' 
  AND token = 'MstkBi705tL5ek9x5/gpGNVqTA0yu+7Za6w7vvVg7D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}