SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217500c9dc7898e20263cc717c73bc0abb0f4d556803a11ba0bef9f641102755' 
  AND token = 'ql/D+hR8T+6QN/eT3OyMi1ZXiRFzd86JeixGKE8x3sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}