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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654c614895cd1c4ee6cfdeedfbea20cccd210d2c3725588eb6f0113e4fa8ea09' 
  AND token = 't/t1UTLQ4ZqYoRpY39yfNNC9SUDRihhyiAAuoJizLW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}