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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5febd0dd096c97841572de392b9fee0c33ab9974fd1a82336507bc26bec3ea' 
  AND token = 'jrmgm3TPcUotHFt6C1qzeQxkGMJPU/GRY0Zr3Zjd2K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}