SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2844b5c97b99b5ce962beccb1ff3829bf0fa66c0e2b65b387d127cda08f86cce' 
  AND token = 'SMWvlOKixsTT8nQRXoKkNUi/k/R/sq/9WO7MrU8C/kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}