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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443c3cd9e813fea8d28220e5985d577611d42762b783d153604a328fa96a2c33' 
  AND token = '7fO5G5cO0FRNh6c6OZrB1rgoqN3rJZcC+mgIZRMHIZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}