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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354ad9b0f60c95a553f66a06bcf7b0a5b157f4e6589a7fd5f9c0a23d648105fc' 
  AND token = 'uCX00OfXVUMN8MEwAyV1WMmXYWmwk507uFooTfQMnc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}