SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd833d5eae6a3e44f107eb9a851fdf820a675e284a007ca816d53db13940235a' 
  AND token = 'RNMkYDVDMktacaVvXyR673TglowPxKu+q/yLiYkROn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}