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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07219d35925973225388b2638fe19d344bb466b56b159acd0b1d5016f6af5ad8' 
  AND token = 'EbHVaN8ooEJoVzrQ4xvxF4tCNuLi+RsIDc+5/aeaBY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}