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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80067c2a271801c3b80731b549993031e7cd0905d53fe9bbd20d7e3b49fdc0c1' 
  AND token = 'vR0FZxP0rBxD1ane85Vri35JS2NWORGtWx1coFkl3fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}